The Frontier

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This Week in Startups
This Week in Startups 3d ago
  • Astroforge CEO Matt Gialich argues asteroid mining must shift from NASA-style budgets to lean, repeatable missions targeting near-Earth asteroids.

  • Astroforge's Deep Space 2 mission, launching this year, costs $10.4 million with a potential $105 million return for 1,000kg of platinum-group metals.

  • The company targets over 600,000 cataloged near-Earth asteroids, focusing on 'metal asteroids' with 70% iron-nickel composition.

  • The magnetic surface of iron-nickel asteroids allows Astroforge spacecraft to dock using simple magnets, avoiding complex landing mechanics.

  • In zero gravity, traditional drilling fails due to Newtonian reaction forces, so Astroforge uses directed energy lasers to vaporize asteroid material.

  • Magnetism separates the ore: platinum-group metals are non-magnetic and pass through a filter, while magnetic iron-nickel is diverted.

  • Gialich dismisses in-space manufacturing hubs as premature, stating there is no existing 'in-space economy' to support them.

  • The current strategy is strictly extractive, aiming to return refined platinum-group metals to Earth to replace destructive terrestrial mining.

  • A 10-to-1 return ratio on missions would transform space exploration from a cost center into a profitable commodity cycle.

This Week in Startups 5d ago
  • Bittensor's subnet 68, called Metanova, uses a decentralized network to crowdsource the search for drug molecules that bind to specific biological targets like serotonin receptors, aiming to cut pharmaceutical R&D costs.

  • The project treats drug discovery, a process that typically costs $2.6 billion over a decade, as a distributed computing problem, according to operators Michaela Bazo and Pedro Penna.

  • Miners on subnet 68 compete in two parallel tasks: submitting target-binding molecules or developing the chemical search algorithms to find them, exploring a constrained space of roughly 65 billion synthesizable compounds.

  • Validators score the miner submissions, and winners are paid with token emissions, creating a perpetual, incentivized global hackathon model for pharmaceutical research.

  • Metanova launched in March 2023 as a proof of concept to see if drug discovery could be accomplished in a decentralized way, which operators claimed had never been tried before.

This Week in Startups 5d ago
  • Jake Lusararian of Gecko Robotics argues that deterministic, purpose-built robots for infrastructure inspection represent greater economic value than general-purpose humanoids.

  • Lusararian says the current AI hype cycle is converging with industrial necessity, creating a moment for pragmatic robotics with 13-year head starts.

  • Gecko Robotics' thesis is to gather data from the physical world to predict and prevent infrastructure failures, which Lusararian positions as a foundation for economic growth.

  • Chris Latner, CEO of Modular, identifies a fragmented AI hardware landscape where a lack of software portability stifles innovation by locking developers into vendor-specific toolkits.

  • Latner's company, Modular, aims to build a unifying software layer that allows AI models to run on any hardware, from data centers to edge devices, to break vendor lock-in.

  • Both founders highlight a market shift from speculative AI demos to pragmatic, mission-critical deployment in sectors like energy, defense, and manufacturing.

  • The explosion in AI models has intensified the need for reliable, non-hallucinatory data from physical infrastructure, creating demand for robotics like Gecko's.

End of 7-day edition — 21 results